Offering to Share:
How to Put Heads Together in Autism Neuroimaging

Matthew K Belmonte
John C Mazziotta
Nancy J Minshew
Alan C Evans
Eric Courchesne
Stephen R Dager
Susan Y Bookheimer
Elizabeth H Aylward
David G Amaral
Rita M Cantor
Diane C Chugani
Anders M Dale
Christos Davatzikos
Guido Gerig
Martha R Herbert
Janet E Lainhart
Declan G Murphy
Joseph Piven
Allan L Reiss
Robert T Schultz
Thomas A Zeffiro
Susan Levi-Pearl
Clara Lajonchere
Sophia A Colamarino

Journal of Autism and Developmental Disorders 38(1):2-13 (January 2008).

ABSTRACT

Data sharing in autism neuroimaging presents scientific, technical, and social obstacles. We outline the desiderata for a data-sharing scheme that combines imaging with other measures of phenotype and with genetics, defines requirements for comparability of derived data and recommendations for raw data, outlines a core protocol including multispectral structural and diffusion-tensor imaging and optional extensions, provides for the collection of prospective, confound-free normative data, and extends sharing and collaborative development not only to data but to the analytical tools and methods applied to these data. A theme in these requirements is the need to preserve creative approaches and risk-taking within individual laboratories at the same time as common standards are provided for these laboratories to build on.

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The original publication is available at www.springerlink.com

CITED IN PUBLICATIONS BY OTHERS:

  1. Rapin I, Tuchman RF. What is new in autism? Current Opinion in Neurology 21(2):143-149 (April 2008).
  2. Di Martino A, Ross K, Uddin LQ, Sklar AB, Castellanos FX, Milham MP. Functional brain correlates of social and nonsocial processes in autism spectrum disorders: an activation likelihood estimation meta-analysis. Biological Psychiatry, in press.