NMR Intensity of Corpus Callosum Differs with Age but not with Diagnosis of Autism

Matthew Belmonte, Brian Egaas, Jeanne Townsend, Eric Courchesne

neuroReport 6(9):1253-1256 (19 June 1995).

Address for correspondence: mkb4@cornell.edu

ABSTRACT: NMR signal intensities in five regions of the midsagittal corpus callosum were measured in autism patients and normal controls. An age-related increase in signal was observed in the anterior regions in both groups. No significant differences in intensity were detected between the groups.

To receive a password that will allow you to download a reprint, enter your email address here:

DOWNLOAD REPRINT (requires password)

CITED IN PUBLICATIONS BY OTHERS:

  1. Pfefferbaum A, Lim KO, Desmond JE, Sullivan BV. Thinning of the corpus callosum in older alcoholic men: a magnetic resonance imaging study. Alcoholism: Clinical and Experimental Research 20(4):752-757 (June 1996).
  2. Mac Master FP, Keshavan MS, Dick EL, Rosenberg DR. Corpus callosal signal intensity in treatment-naive pediatric obsessive compulsive disorders. Progress in Neuropsychopharmacology and Biological Psychiatry 23(4):601-612 (May 1999).
  3. Hagelthorn KM, Brown WS, Amano S, Asarnow R. Normal development of bilateral field advantage and evoked potential interhemispheric transmission time. Developmental Neuropsychology 18(1):11-31 (January 2000).
  4. Rumsey JM, Ernst M. Functional neuroimaging of autistic disorders. Mental Retardation and Developmental Disabilities Research Reviews 6(3):171-179 (March 2000).
  5. Brown WS, Paul LK. Cognitive and psychosocial deficits in agenesis of the corpus callosum with normal intelligence. Cognitive Neuropsychiatry 5(2):135-157 (May 2000).
  6. Kwon H, Ow AW, Pedatella KE, Lotspeich LJ, Reiss AL. Voxel-based morphometry elucidates structural neuroanatomy of high-functioning autism and Asperger syndrome. Developmental Medicine and Child Neurology 46(11):760-764 (November 2004).
  7. Rice SA, Bigler ED, Cleavinger HB, Tate DF, Sayer J, McMahon W, Ozonoff S, Lu J, Lainhart JE. Macrocephaly, corpus callosum morphology, and autism. Journal of Child Neurology 20(1):34-41 (January 2005).
  8. Cohen BI. Ammonia (NH3), nitric oxide (NO) and nitrous oxide (N2O) — the connection with infantile autism. Autism 10(2):221-223 (March 2006).
  9. Kilian S, Brown WS, Hallam BJ, McMahon W, Lu J, Johnson M, Bigler ED, Lainhart J. Regional callosal morphology in autism and macrocephaly. Developmental Neuropsychology 33(1):74-99 (January-February 2008).

CITED IN MY OTHER PUBLICATIONS:

  1. Belmonte MK, Cook EH, Anderson GM, Rubenstein JL, Greenough WT, Beckel-Mitchener A, Courchesne E, Boulanger LM, Powell SB, Levitt PR, Perry EK, Jiang YH, DeLorey TM, Tierney E. Autism as a disorder of neural information processing: directions for research and targets for therapy. Molecular Psychiatry 9(7):646-663 (July 2004). Unabridged edition at http://www.cureautismnow.org/conferences/summitmeetings/